TORNA ALL’ELENCO

What factors affect the quality of bowel preparation for colonoscopy? A multicenter prospective cohort study in Digestive and Liver Disease

2011
AOU Città della Salute di Torino

Tipo pubblicazione

Conference Abstract

Autori/Collaboratori (19)Vedi tutti...

Bruno M

Rondonotti E

Hassan C


et alii...

Abstract

Background and aim: Aim of this study was to identify factors that impact on the quality of bowel preparation and those that are associated with low patient acceptance. Material and methods: Adult outpatients referred for colonoscopy at 18 Italian centers were enrolled between May and September 2010. The following data were recorded for each patient: age and gender, body mass index, level of education, source of referral and indication for colonoscopy, medical history and current medications. The patients chose freely one of the scheduled types of bowel preparation available in each center, and the type and timing of bowel preparation, the type of instructions provided and patient compliance with the cleansing protocol were recorded. The quality of bowel cleansing was assessed using a previously validated (Rex D, et al GIE 2006) 4-point scale based on the amount and nature of residual material. For statistical analysis, bowel scores were grouped as adequate or inadequate. Data were evaluated by univariate and multivariate logistic regression analysis. Results: Of 2811 outpatients who were enrolled, inadequate colonic preparation was observed in 925 (32.9%) colonoscopies. At multivariate analysis, inadequate cleansing was associated with male gender, previous colonoscopy and a history of cirrhosis, diabetes or chronic invalidating co-morbidities. Conversely, good predictors of adequate preparation were: adherence to bowel preparation (>75% of the recommended dose), use of sennosides or bisacodyl, an interval of less than 12 hours between the completion of bowel preparation and colonoscopy, a BMI of <25, a higher level of education the level of received instructions and the tolerability of preparation (patient's willingness to repeat the same protocol in future). Difficulty in drinking the entire volume and bad taste of the solution were reported by 26.4 and 21.4% of patients, respectively. Both items were associated with inadequate bowel cleansing at univariat

DOI : 10.1016/S1590-8658(11)60148-5

Keywords

multivariate logistic regression analysis; body mass; statistical analysis; patient compliance; medical history; adult; univariate analysis; taste; outpatient; education; gender; intestine; patient; cleaning; health care organization; cohort analysis; gastrointestinal disease; intestine preparation; colonoscopy; bisacodyl; multivariate analysis; male; liver cirrhosis; diabetes mellitus; morbidity; recommended drug dose; drinking; drug therapy;