Purple bag urine syndrome: An uncommon hue in Anticancer Research
2019
ASL Torino 4
Tipo pubblicazione
Conference Abstract
Autori/Collaboratori (9)Vedi tutti...
Olivieri V
Fortunati V
Ollino M
et alii...
Abstract
Background: Purple urine bag syndrome (PUBS) is an uncommon clinical condition in Urology frequently linked to catheter associated infections (1). It is characterized by a bright purple discoloration of the urine usually affecting patients with limited mobility, long-term catheter and multiple comorbidities. Although considered as a benign phenomenon, it is often associated with increasing anxiety in patient, families and clinicians due to the uncommon color of the urine which is caused by specific bacteria. There are debates regarding how aggressively to treat this condition, but no official guidelines are actually available: reassurance of the patient, early antibiotic regimen and changing of chateter are suggested. We report the case of a palliative patient presenting with this rare condition. Case Report: A 80-year-old caucasian female with a past history of breast and renal cancer was hospitalized in an Oncology facility for a strong back pain. On anamnesis she was affected by ageassociated comorbidities such as osteoporosis, diabetes, arterial hypertension and chronic obstructive pulmonary disease; she also underwent a left radical nephrectomy for oncocytoma. Moreover, two years earlier she underwent a right quadrantectomy with extended lymph nodes dissection due to a breast cancer: histological report revealed an invasive ductal carcinoma pT2 pN0 cM0 Ki67 28% Erb >95% and she underwent adjuvant radiotherapy and chemotherapy with tamoxifen. She reported always good conditions so disappointed the last oncological follow up: she recently developed a back pain associated to legs hyposthenia, highly suspected for vertebral fracture. According to her past anamnesis total body contrast enhanced computerized tomography was performed. The examination showed multiple vertebral column metastases and pain was automatically referred to bone pathologic fracture. During hospitalization she received best supportive care and an in-dewelling catheter in order to guarant
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Keywords
creatinine; endogenous compound; gentamicin; indirubin; levofloxacin; mannose; methionine; phosphatase; sulfatase; tamoxifen; unclassified drug; adjuvant radiotherapy; adverse device effect; aged; alkalinity; anamnesis; antibiotic resistance; antibiotic therapy; anxiety; backache; blood examination; breast cancer; breast carcinoma; cancer adjuvant therapy; cancer patient; cancer prognosis; cancer surgery; case report; catheter infection; catheterization; Caucasian; chronic obstructive lung disease; clinical article; clinician; comorbidity; complication; computer assisted tomography; conference abstract; contrast enhancement; diabetes mellitus; drug combination; drug therapy; Escherichia coli; female; follow up; gender; histopathology; hospitalization; human; human tissue; hydration; hydronephrosis; hypertension; immobility; incidence; infectious agent; intravenous drug administration; kidney cancer; Klebsiella; leg; limited mobility; lymph node dissection; male; mortality risk; nonhuman; normal value; oncocytoma; oncology; osteoporosis; partial mastectomy; pathologic fracture; polymerase chain reaction; practice guideline; prognosis; Proteus; Pseudomonas aeruginosa; radical nephrectomy; reassurance; risk factor; spine fracture; spine metastasis; surgery; tryptophan metabolism; ultrasound; urinalysis; urinary catheter; urinary tract infection; urine acidification; urine bag; urine culture; velocity; very elderly;