Clinical Attributes and Risk Factors for Mechanical Ventilation and In- Hospital Mortality Among Hispanic Patients with Covid-19 in a Community Hospital Setting: A Propensity Matched Analysis in American Journal of Respiratory and Critical Care Medicine
2022
ASL Asti
Tipo pubblicazione
Conference Abstract
Autori/Collaboratori (28)Vedi tutti...
Shah J
Del Rio T
Irrizzary L
et alii...
Abstract
Introduction: Covid 19 caused by novel Coronavirus SARS-CoV-2 can present with a wide variety of clinical manifestations including asymptomatic illness, severe respiratory failure, shock, multiorgan failure and death. There is limited information exploring the impact of COVID 19 on certain vulnerable populations. We sought to identify admission clinical attributes and risk factors for mechanical ventilation (MV) and in- hospital mortality among Hispanic patients in a community hospital setting. Methods We performed a retrospective review via electronic medical records (EMR) of hospitalized patients with covid 19 in our institution from March 1st to June 21st, 2020. The cohort comprised of 364 Hispanic patients and 304 non-Hispanic patients. We propensity matched patients 289 Hispanic patients with 289 non- Hispanic in our institution. Matching covariates included Age, Gender, Hypertension, Body Mass Index, and Diabetes Mellitus. Information analyzed included demographics, presenting symptoms, past medical history, admission vital signs, and laboratory data. The admission clinical attributes and laboratory parameters for MV and in-hospital mortality were observed. Logistic regression models were created for in-hospital mortality and MV. Results The mean age of the cohort was 62.2 years. After propensity matching, Hispanic patients had, higher alkaline phosphatase (ALP) > 83 (u/l) (p = .006), lower white blood cell count (WBC) (k / ul) < 8.42 (p = .037), elevated platelet count > 210 (k/ ul) (p = .046). There was no difference in MV (P = 1) and in-hospital mortality (p = .445) between either group. On multivariate logistic regression for both groups, respiratory Rate (RR) > 24 (OR = 2.63, p = <.0001), Albumin < 3 mg/dl (OR = 1.62, p = 0.02), low WBC count (OR = 2.1, p = .001), HR > 125 (OR = 2.39, p = .002) had a higher likelihood for MV. Similarly, RR > 24 (OR = 2.62, p = <.0001), Albumin < 3 mg/dl (OR = 1.65, p = 0.008), low WBC count < 8.42 (OR = 1.54, p = .
DOI : 10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A2971
Keywords
Hispanic; gender; female; electronic medical record; vital sign; middle aged; platelet count; retrospective study; risk factor; medical history; major clinical study; male; leukocyte count; in-hospital mortality; hypertension; diabetes mellitus; demographics; coronavirus disease 2019; conference abstract; community hospital; cohort analysis; case study; breathing rate; body mass; artificial ventilation; adult; endogenous compound; alkaline phosphatase; albumin; human; hospital patient;