Gender Differences and Quality of Life in Parkinson's Disease. in International journal of environmental research and public health / Int J Environ Res Public Health. 2020 Dec 29;18(1):198. doi: 10.3390/ijerph18010198.
2020
ASL Torino 3
Tipo pubblicazione
Review
Autori/Collaboratori (10)Vedi tutti...
Vacante M
Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy.
Marranzano M
Department of Medical, Surgical and Advanced Sciences, University of Catania, 95123 Catania, Italy.
Biondi A
Department of General Surgery and Medical-Surgical Specialties, University of Catania, 95123 Catania, Italy.
et alii...
Abstract
Parkinson's disease has been found to significantly affect health-related quality of life. The gender differences of the health-related quality of life of subjects with Parkinson's disease have been observed in a number of studies. These differences have been reported in terms of the age at onset, clinical manifestations, and response to therapy. In general, women with Parkinson's disease showed more positive disease outcomes with regard to emotion processing, non-motor symptoms, and cognitive functions, although women report more Parkinson's disease-related clinical manifestations. Female gender predicted poor physical functioning and socioemotional health-related quality of life, while male gender predicted the cognitive domain of health-related quality of life. Some studies reported gender differences in the association between health-related quality of life and non-motor symptoms. Depression and fatigue were the main causes of poorer health-related quality of life in women, even in the early stages of Parkinson's disease. The aim of this review was to collect the best available evidence on gender differences in the development of Parkinson's disease symptoms and health-related quality of life.
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PMID : 33383855
DOI : 10.3390/ijerph18010198
Keywords
gender; levodopa; dopamine; Parkinson’s disease; Sex Factors; Quality of Life; Parkinson Disease/epidemiology; Male; Humans; Female; Fatigue; Depression; Activities of Daily Living; quality of life;