Gender-related presentation, surgical treatment, outcome and failure to rescue after surgery for type A aortic dissection: results from a multicentre registry. in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery / Eur J Cardiothorac Surg. 2022 Aug 3;62(3):ezac218. doi: 10.1093/ejcts/ezac218.
2022
AOU Città della Salute di Torino
Tipo pubblicazione
Multicenter Study
Autori/Collaboratori (11)Vedi tutti...
Onorati F
Department of Surgery, Dentistry, Paediatrics, and Gynaecology; Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy.
Faggian G
Department of Surgery, Dentistry, Paediatrics, and Gynaecology; Division of Cardiac Surgery, University of Verona Medical School, Verona, Italy.
Pappalardo A
Azienda Sanitaria Universitaria Giuliana Isontina, Trieste, Italy.
et alii...
Abstract
OBJECTIVES: Reports on gender-related differences in perioperative characteristics and the outcome after surgery for type A acute aortic dissection are contradictory. METHODS: Perioperative characteristics, outcome and overall or itemized failure-to-rescue rates were collected retrospectively and dichotomized by gender in patients operated on at 5 referral institutions. A propensity score matched analysis was performed to compared males and females with similar preoperative risk profiles. Multivariable analysis assessed gender-related predictors of 30-day mortality. RESULTS: A total of 1271 patients were collected. Females (on average, 63?years old) developed type A acute aortic dissection, with differences in clinical presentation (number of intimal tears, thoracic pain at the onset of symptoms). Female-reported characteristics included lower frozen elephant trunk and elephant trunk procedures, higher femoral perfusion, retrograde cerebral perfusion and retrograde cardiopulmonary bypass restart after deep hypothermic circulatory arrest (P?
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PMID : 35640136
DOI : 10.1093/ejcts/ezac218
Keywords
neurological dysfunction; gender; failure to rescue; coma; acute kidney injury; acute aortic dissection; Treatment Outcome; Risk Factors; Retrospective Studies; Middle Aged; Registries; Humans; Male; Female; Coma/surgery; Blood Vessel Prosthesis Implantation/methods; Aortic Aneurysm, Thoracic/surgery; Aortic Dissection; Aorta, Thoracic/surgery;