TORNA ALL’ELENCO

Impact of gender on 10-year outcome after coronary artery bypass grafting. in Interactive cardiovascular and thoracic surgery / Interact Cardiovasc Thorac Surg. 2021 Oct 4;33(4):510-517. doi: 10.1093/icvts/ivab125.

2021
AOU Città della Salute di Torino

Tipo pubblicazione

Research Support, Non-U.S. Gov't

Autori/Collaboratori (10)Vedi tutti...

Seccareccia F
National Centre for Global Health, Italian Health Institute, Rome, Italy.
Badoni G
Unit of Cardiac Surgery, IRCCS Policlinico S. Donato, University of Milan, S. Donato Milanese, Italy.
Gellini M
Department of Epidemiology, Città della Salute e della Scienza, University of Turin, Turin, Italy.

et alii...

Abstract

OBJECTIVES: Our goal was to evaluate the impact of gender on the 10-year outcome of patients after isolated coronary artery bypass grafting (CABG) included in the Italian nationwide PRedictIng long-term Outcomes afteR Isolated coronary arTery bypass surgery (PRIORITY) study. METHODS: The PRIORITY project was designed to evaluate the long-term outcomes of patients who underwent CABG and were included in 2 prospective multicentre cohort studies. The primary end point of this analysis was major adverse cardiac and cerebrovascular events. Baseline differences between the study groups were balanced with propensity score matching and inverse probability of treatment. Time to events was analysed using Cox regression and competing risk analysis. RESULTS: The study population comprised 10?989 patients who underwent isolated CABG (women 19.6%). Propensity score matching produced 1898 well-balanced pairs. The hazard of major adverse cardiac and cerebrovascular event was higher in women compared to men [adjusted hazard ratio (HR) 1.13, 95% confidence interval (CI) 1.03-1.23; P?=?0.009]. The incidence of major adverse cardiac and cerebrovascular event in women was significantly higher at 1?year (HR 1.31, 95% CI 1.11-1.55; P?

PMID : 34000041

DOI : 10.1093/icvts/ivab125

Keywords

Women; Gender; Female; Coronary artery bypass grafting; Risk Factors; Treatment Outcome; Retrospective Studies; Prospective Studies; Propensity Score; Male; Percutaneous Coronary Intervention; Female; Humans; Coronary Artery Disease/surgery; Coronary Artery Bypass/adverse effects;