What to Know about Antimicrobial Coatings in Arthroplasty: A Narrative Review. in Medicina (Kaunas, Lithuania) / Medicina (Kaunas). 2024 Mar 30;60(4):574. doi: 10.3390/medicina60040574.

2024
ASL Cuneo 1

Tipo pubblicazione

Review

Autori/Collaboratori (5)Vedi tutti...

Onorato F
Department of Orthopedics and Traumatology, University of Turin, Via Zuretti, 29, 10126 Turin, Italy.
Masoni V
Department of Orthopedics and Traumatology, University of Turin, Via Zuretti, 29, 10126 Turin, Italy.
Gagliardi L
Department of Orthopedics and Traumatology, University of Turin, Via Zuretti, 29, 10126 Turin, Italy.

et alii...

Abstract

Periprosthetic joint infections (PJIs) are one of the most worrying complications orthopedic surgeons could face; thus, methods to prevent them are evolving. Apart from systemic antibiotics, targeted strategies such as local antimicrobial coatings applied to prosthetics have been introduced. This narrative review aims to provide an overview of the main antimicrobial coatings available in arthroplasty orthopedic surgery practice. The search was performed on the PubMed, Web of Science, SCOPUS, and EMBASE databases, focusing on antimicrobial-coated devices used in clinical practice in the arthroplasty world. While silver technology has been widely adopted in the prosthetic oncological field with favorable outcomes, recently, silver associated with hydroxyapatite for cementless fixation, antibiotic-loaded hydrogel coatings, and iodine coatings have all been employed with promising protective results against PJIs. However, challenges persist, with each material having strengths and weaknesses under investigation. Therefore, this narrative review emphasizes that further clinical studies are needed to understand whether antimicrobial coatings can truly revolutionize the field of PJIs.

Accesso banca dati bibliografica

PMID : 38674220

DOI : 10.3390/medicina60040574

Keywords

Humans; Prosthesis-Related Infections/prevention & control; Anti-Infective Agents/therapeutic use/administration & dosage; Arthroplasty/methods; Coated Materials, Biocompatible; Silver/pharmacology; antimicrobial coatings; arthroplasty; clinical practice; narrative review; periprosthetic joint infections;