Morphologic Features of Invasion in Lung Adenocarcinoma: Diagnostic Pitfalls. in Advances in anatomic pathology / Adv Anat Pathol. 2024 May 13. doi: 10.1097/PAP.0000000000000451.
2024
ASL Cuneo 2
ASL Cuneo 2
Tipo pubblicazione
Journal Article
Autori/Collaboratori (7)Vedi tutti...
Thunnissen E
Department of Pathology, Amsterdam University Medical Center, Location Vumc.
Noguchi M
Department of Pathology, Naritatomisato Tokushukai Hospital, Chiba.
Berezowska S
Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
et alii...
Department of Pathology, Amsterdam University Medical Center, Location Vumc.
Noguchi M
Department of Pathology, Naritatomisato Tokushukai Hospital, Chiba.
Berezowska S
Department of Laboratory Medicine and Pathology, Institute of Pathology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
et alii...
Abstract
Reproducibility of pulmonary invasive adenocarcinoma diagnosis is poor when applying the World Health Organization (WHO) classification. In this article, we aimed first to explain by 3-dimensional morphology why simple pattern recognition induces pitfalls for the assessment of invasion as applied in the current WHO classification of pulmonary adenocarcinomas. The underlying iatrogenic-induced morphologic alterations in collapsed adenocarcinoma in situ overlap with criteria for invasive adenocarcinoma. Pitfalls in seemingly acinar and papillary carcinoma are addressed with additional cytokeratin 7 and elastin stains. In addition, we provide more stringent criteria for a better reproducible and likely generalizable classification.
Accesso banca dati bibliografica
Accedi alla scheda bibliografica del documento in PUBMED
Se sei accreditato in BVS-P effettua prima l'accesso per utilizzare i nostri servizi.
PMID : 38736358
DOI : 10.1097/PAP.0000000000000451