Italian guidelines for the management of adult individuals with overweight and obesity and metabolic comorbidities that are resistant to behavioral treatment. in Journal of endocrinological investigation / J Endocrinol Invest. 2024 Jun;47(6):1361-1371. doi: 10.1007/s40618-024-02361-y. Epub 2024 Apr 17.
2024
ASL Novara
Tipo pubblicazione
Systematic Review
Autori/Collaboratori (35)Vedi tutti...
Chianelli M
Endocrinology, Regina Apostolorum Hospital, Albano Laziale, RM, Italy.
Busetto L
Department of Medicine, Center for Medical and Surgical Therapy of Obesity, University of Padua, Padua University Hospital, President of the Italian Society for Obesity, Padua, Italy.
Vettor R
Department of Medicine, Medical Clinic 3rd, Endocrine-Metabolic Unit, Padua University Hospital, Center for the Study and Integrated Treatment of Obesity, University of Padua, Padua, Italy.

et alii...
Abstract
AIM: This guideline (GL) is aimed at providing a clinical practice reference for the management of adult patients with overweight or obesity associated with metabolic complications who are resistant to lifestyle modification. METHODS: Surgeons, endocrinologists, gastroenterologists, psychologists, pharmacologists, a general practitioner, a nutritionist, a nurse and a patients' representative acted as multi-disciplinary panel. This GL has been developed following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. A systematic review and network meta-analysis was performed by a methodologic group. For each question, the panel identified potentially relevant outcomes, which were then rated for their impact on therapeutic choices. Only outcomes classified as "critical" and "important" were considered in the systematic review of evidence. Those classified as "critical" were considered for clinical practice recommendations. Consensus on the direction (for or against) and strength (strong or conditional) of recommendations was reached through a majority vote. RESULTS: The present GL provides recommendations about the role of both pharmacological and surgical treatment for the clinical management of the adult patient population with BMI?>?27 kg/m(2) and?
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PMID : 38630213
DOI : 10.1007/s40618-024-02361-y
Keywords
Humans; Obesity/therapy/complications/epidemiology; Overweight/therapy/complications/epidemiology; Adult; Italy/epidemiology; Comorbidity; Behavior Therapy/methods/standards; Practice Guidelines as Topic/standards; Disease Management; Bariatric Surgery/methods; Bariatric surgery; Liraglutide; Naltrexone–bupropion; Obesity; Orlistat; Semaglutide;