Hospitalisation for herpes zoster in people with and without diabetes: A 10-year-observational study. in Diabetes research and clinical practice / Diabetes Res Clin Pract. 2024 Apr;210:111603. doi: 10.1016/j.diabres.2024.111603. Epub 2024 Mar 8.

2024
ASL Torino 5
ASL Torino 3

Tipo pubblicazione

Observational Study

Autori/Collaboratori (7)Vedi tutti...

Gnavi R
Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy.
Costa G
Epidemiology Unit, ASL TO3, Regione Piemonte, Grugliasco, Italy; Department of Public Health, University of Torino, Torino, Italy.
Romeo F
Metabolism and Diabetes Unit, ASL TO5, Regione Piemonte, Chieri, Italy.

et alii...

Abstract

AIMS: This study explores the association between Herpes Zoster (HZ) hospitalizations and diabetes in Piedmont, Italy from 2010 to 2019. Focusing on the burden of HZ hospitalizations in diabetic and non-diabetic groups, it aims to identify risk factors in diabetics to enhance prevention strategies. METHODS: In a two-phase study, we first compared age-standardized HZ hospitalization rates between diabetic and non-diabetic individuals from 2010 to 2019. We then examined hospitalization risk factors for HZ within a diabetic patient cohort managed by regional diabetes clinics. RESULTS: Of 3,423 HZ hospitalizations in 2010-2019, 17.9 % (613 cases) were diabetic patients, who exhibited higher hospitalization rates (15.9 to 6.0 per 100,000) compared to non-diabetese individuals. Among diabetics subjects risk factors for HZ hospitalization included age over 65, obesity (BMI > 30), and poor glycemic control (HbA1c > 8.0 %). These patients had a 40 % increased rehospitalization risk and a 25 % higher risk of severe complications, such as stroke and myocardial infarction, post-HZ. CONCLUSIONS: Diabetes markedly increases HZ hospitalization rates, rehospitalization, and complication risks. These findings underscore the need for preventive strategies, especially improved glycemic control among high-risk diabetic patients, to inform public health policies and clinical practices aimed at mitigating HZ's impact on this population.

Accesso banca dati bibliografica

PMID : 38460790

DOI : 10.1016/j.diabres.2024.111603

Keywords

Hospitalization; Diabetes; Diabetes complications; Hospital stay and recurrence; Metabolic control; Zoster infection hospitalization; Herpesvirus 3, Human; Retrospective Studies; Herpes Zoster/epidemiology; Humans; Diabetes Mellitus/epidemiology;