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Sfoglia per AUTORE
LEONARDUZZI G
Collezione AOU San Luigi di Orbassano

Items : 33

The Emerging Role of PCSK9 in the Pathogenesis of Alzheimer's Disease: A Possible Target for the Disease Treatment. in International journal of molecular sciences / Int J Mol Sci. 2024 Dec 20;25(24):13637. doi: 10.3390/ijms252413637.

2024
AOU San Luigi di Orbassano

Testa G; Giannelli S; Staurenghi E; Cecci R; Floro L; Gamba P; Sottero B; Leonarduzzi G;

Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease. in Antioxidants (Basel, Switzerland) / Antioxidants (Basel). 2024 Apr 3;13(4):435. doi: 10.3390/antiox13040435.

2024
AOU San Luigi di Orbassano

Staurenghi E; Testa G; Leoni V; Cecci R; Floro L; Giannelli S; Barone E; Perluigi M; Leonarduzzi G; Sottero B; Gamba P;

Implication of oxysterols in chronic inflammatory human diseases. in Biochimie / Biochimie. 2018 Oct;153:220-231. doi: 10.1016/j.biochi.2018.06.006. Epub 2018 Jun 9.

2018
AOU San Luigi di Orbassano

Testa G; Rossin D; Poli G; Biasi F; Leonarduzzi G;

Oxysterols and 4-hydroxy-2-nonenal contribute to atherosclerotic plaque destabilization. in Free radical biology & medicine / Free Radic Biol Med. 2017 Oct;111:140-150. doi: 10.1016/j.freeradbiomed.2016.12.037. Epub 2017 Jan 3

2017
AOU San Luigi di Orbassano

Gargiulo S; Testa G; Gamba P; Staurenghi E; Poli G; Leonarduzzi G;

Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation. in Redox biology / Redox Biol. 2016 Dec;10:24-33. doi: 10.1016/j.redox.2016.09.001. Epub 2016 Sep 16.

2016
AOU San Luigi di Orbassano

Testa G; Staurenghi E; Zerbinati C; Gargiulo S; Iuliano L; Giaccone G; Fantò F; Poli G; Leonarduzzi G; Gamba P;

The role of oxysterols in vascular ageing. in The Journal of physiology / J Physiol. 2016 Apr 15;594(8):2095-113. doi: 10.1113/JP271168. Epub 2016 Jan 19.

2016
AOU San Luigi di Orbassano

Gargiulo S; Gamba P; Testa G; Leonarduzzi G; Poli G;

Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol. in Scientific reports / Sci Rep. 2014 Dec 15;4:7487. doi: 10.1038/srep07487.

2014
AOU San Luigi di Orbassano

Civra A; Cagno V; Donalisio M; Biasi F; Leonarduzzi G; Poli G; Lembo D;

Metalloproteinases and metalloproteinase inhibitors in age-related diseases. in Current pharmaceutical design / Curr Pharm Des. 2014;20(18):2993-3018. doi: 10.2174/13816128113196660701.

2014
AOU San Luigi di Orbassano

Gargiulo S; Gamba P; Poli G; Leonarduzzi G;

Wine consumption and intestinal redox homeostasis. in Redox biology / Redox Biol. 2014 Jun 18;2:795-802. doi: 10.1016/j.redox.2014.06.008. eCollection 2014.

2014
AOU San Luigi di Orbassano

Biasi F; Deiana M; Guina T; Gamba P; Leonarduzzi G; Poli G;

Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets. in Antioxidants & redox signaling / Antioxid Redox Signal. 2013 Nov 10;19(14):1711-47. doi: 10.1089/ars.2012.4530. Epub 2013 Mar 1.

2013
AOU San Luigi di Orbassano

Biasi F; Leonarduzzi G; Oteiza PI; Poli G;

Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line. in Biochimie / Biochimie. 2013 Mar;95(3):632-40. doi: 10.1016/j.biochi.2012.10.011. Epub 2012 Oct 22.

2013
AOU San Luigi di Orbassano

Biasi F; Chiarpotto E; Sottero B; Maina M; Mascia C; Guina T; Gamba P; Gargiulo S; Testa G; Leonarduzzi G; Poli G;

Molecular signaling involved in oxysterol-induced ??-integrin over-expression in human macrophages. in International journal of molecular sciences / Int J Mol Sci. 2012 Nov 5;13(11):14278-93. doi: 10.3390/ijms131114278.

2012
AOU San Luigi di Orbassano

Gargiulo S; Gamba P; Testa G; Sottero B; Maina M; Guina T; Biasi F; Poli G; Leonarduzzi G;

Progressive increase of matrix metalloprotease-9 and interleukin-8 serum levels during carcinogenic process in human colorectal tract. in PloS one / PLoS One. 2012;7(7):e41839. doi: 10.1371/journal.pone.0041839. Epub 2012 Jul 25.

2012
AOU San Luigi di Orbassano

Biasi F; Guina T; Maina M; Nano M; Falcone A; Aroasio E; Saracco GM; Papotti M; Leonarduzzi G; Poli G;

Polyphenol supplementation as a complementary medicinal approach to treating inflammatory bowel disease. in Current medicinal chemistry / Curr Med Chem. 2011;18(31):4851-65. doi: 10.2174/092986711797535263.

2011
AOU San Luigi di Orbassano

Biasi F; Astegiano M; Maina M; Leonarduzzi G; Poli G;

Targeting tissue oxidative damage by means of cell signaling modulators: the antioxidant concept revisited. in Pharmacology & therapeutics / Pharmacol Ther. 2010 Nov;128(2):336-74. doi: 10.1016/j.pharmthera.2010.08.003. Epub 2010 Aug 21.

2010
AOU San Luigi di Orbassano

Leonarduzzi G; Sottero B; Poli G;

Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells. in Molecular nutrition & food research / Mol Nutr Food Res. 2010 May;54 Suppl 1:S31-41. doi: 10.1002/mnfr.200900493.

2010
AOU San Luigi di Orbassano

Leonarduzzi G; Gargiulo S; Gamba P; Perrelli MG; Castellano I; Sapino A; Sottero B; Poli G;

Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids. in Current medicinal chemistry / Curr Med Chem. 2010;17(1):74-95. doi: 10.2174/092986710789957760.

2010
AOU San Luigi di Orbassano

Leonarduzzi G; Testa G; Sottero B; Gamba P; Poli G;

Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression. in Free radical biology & medicine / Free Radic Biol Med. 2009 Dec 15;47(12):1731-41. doi: 10.1016/j.freeradbiomed.2009.09.020. Epub 2009

2009
AOU San Luigi di Orbassano

Biasi F; Mascia C; Astegiano M; Chiarpotto E; Nano M; Vizio B; Leonarduzzi G; Poli G;

Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry. in Current medicinal chemistry / Curr Med Chem. 2009;16(6):685-705. doi: 10.2174/092986709787458353.

2009
AOU San Luigi di Orbassano

Sottero B; Gamba P; Gargiulo S; Leonarduzzi G; Poli G;

4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases. in Molecular aspects of medicine / Mol Aspects Med. 2008 Feb-Apr;29(1-2):67-71. doi: 10.1016/j.mam.2007.09.016. Epub 2007 Nov 21.

2008
AOU San Luigi di Orbassano

Poli G; Biasi F; Leonarduzzi G; Poli G; Biasi F; Leonarduzzi G;

Activation of the mitochondrial pathway of apoptosis by oxysterols. in Frontiers in bioscience : a journal and virtual library / Front Biosci. 2007 Jan 1;12:791-9. doi: 10.2741/2102.

2007
AOU San Luigi di Orbassano

Leonarduzzi G; Poli G; Sottero B; Biasi F;

Lipid peroxidation and inflammatory molecules as markers of coronary artery disease. in Redox report : communications in free radical research / Redox Rep. 2007;12(1):81-5. doi: 10.1179/135100007X162275.

2007
AOU San Luigi di Orbassano

Sottero B; Pozzi R; Leonarduzzi G; Aroasio E; Gamba P; Gargiulo S; Rabajoli F; Ferrari F; Greco Lucchina P; Poli G;

c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa. in Free radical biology & medicine / Free Radic Biol Med. 2006 Aug 1;41(3):443-54. doi: 10.1016/j.freeradbiomed.2006.04.005. Epub 2006 Ap

2006
AOU San Luigi di Orbassano

Biasi F; Vizio B; Mascia C; Gaia E; Zarkovic N; Chiarpotto E; Leonarduzzi G; Poli G;

Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells. in Free radical biology & medicine / Free Radic Biol Med. 2005 Nov 1;39(9):1152-61. doi: 10.1016/j.freeradbiomed.2005.06.024. Epub 2005 A

2005
AOU San Luigi di Orbassano

Leonarduzzi G; Gamba P; Sottero B; Kadl A; Robbesyn F; Calogero RA; Biasi F; Chiarpotto E; Leitinger N; Sevanian A; Poli G;

Expression and synthesis of TGFbeta1 is induced in macrophages by 9-oxononanoyl cholesterol, a major cholesteryl ester oxidation product. in BioFactors (Oxford, England) / Biofactors. 2005;24(1-4):209-16. doi: 10.1002/biof.5520240125.

2005
AOU San Luigi di Orbassano

Sottero B; Gamba P; Longhi M; Robbesyn F; Abuja PM; Schaur RJ; Poli G; Leonarduzzi G;

Oxidative stress and cell signalling. in Current medicinal chemistry / Curr Med Chem. 2004 May;11(9):1163-82. doi: 10.2174/0929867043365323.

2004
AOU San Luigi di Orbassano

Poli G; Leonarduzzi G; Biasi F; Chiarpotto E;

Trojan horse-like behavior of a biologically representative mixture of oxysterols. in Molecular aspects of medicine / Mol Aspects Med. 2004 Feb-Apr;25(1-2):155-67. doi: 10.1016/j.mam.2004.02.016.

2004
AOU San Luigi di Orbassano

Leonarduzzi G; Biasi F; Chiarpotto E; Poli G;

Signaling kinases modulated by 4-hydroxynonenal. in Free radical biology & medicine / Free Radic Biol Med. 2004 Dec 1;37(11):1694-702. doi: 10.1016/j.freeradbiomed.2004.08.027.

2004
AOU San Luigi di Orbassano

Leonarduzzi G; Robbesyn F; Poli G;

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review). in The Journal of nutritional biochemistry / J Nutr Biochem. 2002 Dec;13(12):700-710. doi: 10.1016/s0955-2863(02)00222-x.

2002
AOU San Luigi di Orbassano

Leonarduzzi G; Sottero B; Poli G;

Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology / FASEB J. 2001 Jul;15(9):1619-21. doi: 10.1096/fj.00-0668fje.

2001
AOU San Luigi di Orbassano

Leonarduzzi G; Sevanian A; Sottero B; Arkan MC; Biasi F; Chiarpotto E; Basaga H; Poli G;

Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage. in Free radical biology & medicine / Free Radic Biol Med. 2001 Aug 1;31(3):374-82. doi: 10.1016/s0891-5849(01)00601-3.

2001
AOU San Luigi di Orbassano

Arkan MC; Leonarduzzi G; Biasi F; Ba?a?a H; Poli G;

Cholesterol oxidation products and fibrogenesis. in BioFactors (Oxford, England) / Biofactors. 2001;15(2-4):117-9. doi: 10.1002/biof.5520150214.

2001
AOU San Luigi di Orbassano

Leonarduzzi G; Sevanian A; Poli G;

Lipid oxidation products in cell signaling. in Free radical biology & medicine / Free Radic Biol Med. 2000 May 1;28(9):1370-8. doi: 10.1016/s0891-5849(00)00216-1.

2000
AOU San Luigi di Orbassano

Leonarduzzi G; Arkan MC; Ba?a?a H; Chiarpotto E; Sevanian A; Poli G;